Core API Regulation API 1 0..* Coordinates 1 0..* get_all_RegulatoryFeatureVariations get_all_TranscriptVariations 1 1 0..* 0..* 1 1 1..* 1..* get_all_RegulatoryFeatureVariationAlleles get_all_TranscriptVariationAlleles 1 1 1..* 1..* get_all_OverlapConsequences Allele get_all_Alleles 1 1..* get_all_PopulationGenotypes get_all_SampleGenotypes Genotype 1 1 0..* EnsEMBL Variation API Overview - Variation centered slice transcript 1 1..* 1 1..* 1..* 1 regulatory_feature get_all_VariationFeatures Phenotype get_all_PhenotypeFeatures population 0..1 1..* population 1..* 1 PhenotypeFeature (phenotype, location, other annotations) Allele (allele, frequency, population) SampleGenotype PopulationGenotype Variation Population (e.g. 1000GENOMES:phase_3:CEU) RegulatoryFeature (e.g. chromosome:1:200-300) Bio::EnsEMBL::Variation Bio::EnsEMBL Bio::EnsEMBL::Funcgen VariationFeature (genomic location) TranscriptVariation (location in transcript and protein) Slice (e.g. chromosome:1:250-250) Transcript (e.g. ENST00000393489) TranscriptVariationAllele (allelic effect on transcript, codon, peptide and protein prediction) OverlapConsequence (consequence terms: e.g.: missense_variant) RegulatoryFeatureVariation (location in regulatory element) RegulatoryFeatureVariationAllele (allelic information on a regulatory element) Central class Feature class Class from a different Ensembl API Get object(s) from the same API Get object(s) from a different API text Method to get the object(s) Legend slice 0..1 Publication (PubMed ID, Title) 1..* 0..* 0..* Citation get_all_Publications