peak-motifs Astrocytes_MDD_off_on_drugs

Sequence composition (test sequences)

Nb of peaks: 26
Total seq. size: 21 kb
Min length: 208 bp
Mean length: 798.192 bp
Max length: 1000 bp [ seq: converted purged ]
[ lengths: list distrib graph ]

Nucleotide composition profiles

Transition frequencies
Position profiles

[ 1nt: freq transitions ]
[ bg model: Inclusive format ]
[ profile: table html(individual) ]

Dinucleotide composition profiles

Transition frequencies
Position profiles

[ 2nt: freq transitions ]
[ bg model: Inclusive format ]
[ profile: table html(individual) ]

Trinucleotide composition profiles

Transition frequencies
Position profiles

[ 3nt: freq transitions ]
[ bg model: Inclusive format ]
[ profile: table html(individual) ]

Motif discovery

Motif 1 oligos_6nt_mkv2_m1

k-mer sig=11.84; evalue=1.4e-12

mmsCCGCSGCSGCGGskk

MMSCCGCSGCSGCGGSKK

[ k-mers: statistics assemblies ]
[ matrix: tab_format transfac_format ]

JASPAR2024_CORE_vertebrates_non-redundant

name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match

columns aligned correlation cor mmsCCGCSGCSGCGGskk

ZNF93 MA1721.2 D 14 0.7778 0.718 0.558 NA NA

Total matches= 1

[ match table: html text ]
[ alignments (logos): html text ]

Predicted sites on test peaks

Distribution of sites

Nb of predicted sites per peak

Nb peaks with at least one predicted site: 2 (7.69%)
Max nb of predicted sites per peak: 119
(chr1:144076366-144077773)
Mean nb of predicted sites per peak: 61.00

[ sites: text ]
[ distribution: text ]
[ sites per peak: text ]
[ enrichment: text graph ]

Motif 2 oligos_6nt_mkv2_m2

k-mer sig=4.87; evalue=1.3e-05

mmGCCGmGGCkk

MMGCCKCGGCKK

[ k-mers: statistics assemblies ]
[ matrix: tab_format transfac_format ]

JASPAR2024_CORE_vertebrates_non-redundant

name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match

columns aligned correlation cor mmGCCGmGGCkk

Zfx MA0146.3 D 10 0.8333 0.722 0.601 NA NA

ZNF213 MA2121.1 D 10 0.7143 0.732 0.523 NA NA

Total matches= 2

[ match table: html text ]
[ alignments (logos): html text ]

Predicted sites on test peaks

Distribution of sites

Nb of predicted sites per peak

Nb peaks with at least one predicted site: 3 (11.54%)
Max nb of predicted sites per peak: 90
(chr1:144076366-144077773)
Mean nb of predicted sites per peak: 33.00

[ sites: text ]
[ distribution: text ]
[ sites per peak: text ]
[ enrichment: text graph ]

Motif 3 oligos_6nt_mkv2_m3

k-mer sig=4.66; evalue=2.2e-05

CaAAAAGCCGCG

CGCGGCTTTTTG

[ k-mers: statistics assemblies ]
[ matrix: tab_format transfac_format ]

JASPAR2024_CORE_vertebrates_non-redundant

name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match

columns aligned correlation cor CaAAAAGCCGCG

Total matches= 0

No match

Predicted sites on test peaks

Distribution of sites

Nb of predicted sites per peak

Nb peaks with at least one predicted site: 1 (3.85%)
Max nb of predicted sites per peak: 42
(chr1:144076366-144077773)
Mean nb of predicted sites per peak: 42.00

[ sites: text ]
[ distribution: text ]
[ sites per peak: text ]
[ enrichment: text graph ]

Motif 4 oligos_6nt_mkv2_m4

k-mer sig=1.18; evalue=0.066

sbCCCACCCcs

SGGGGTGGGVS

[ k-mers: statistics assemblies ]
[ matrix: tab_format transfac_format ]

JASPAR2024_CORE_vertebrates_non-redundant

name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match

columns aligned correlation cor sbCCCACCCcs

PATZ1 MA1961.2 R 11 1.0000 0.846 0.846 NA NA

KLF5 MA0599.1 D 10 0.9091 0.874 0.795 NA NA

KLF16 MA0741.1 D 11 1.0000 0.734 0.734 NA NA

Total matches= 40 (37 more)

[ match table: html text ]
[ alignments (logos): html text ]

Predicted sites on test peaks

Distribution of sites

Nb of predicted sites per peak

Nb peaks with at least one predicted site: 8 (30.77%)
Max nb of predicted sites per peak: 18
(chr1:144076366-144077773)
Mean nb of predicted sites per peak: 4.38

[ sites: text ]
[ distribution: text ]
[ sites per peak: text ]
[ enrichment: text graph ]

Motif 5 oligos_6nt_mkv2_m5

k-mer sig=0.47; evalue=0.34

yyCCTGCCar

YTGGCAGGRR

[ k-mers: statistics assemblies ]
[ matrix: tab_format transfac_format ]

JASPAR2024_CORE_vertebrates_non-redundant

name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match

columns aligned correlation cor yyCCTGCCar

E2F6 MA0471.3 R 8 0.8000 0.734 0.588 NA NA

TCF12 MA1648.2 D 7 0.7000 0.813 0.569 NA NA

ASCL1 MA1631.2 D 8 0.7273 0.777 0.565 NA NA

Total matches= 24 (21 more)

[ match table: html text ]
[ alignments (logos): html text ]

Predicted sites on test peaks

Distribution of sites

Nb of predicted sites per peak

Nb peaks with at least one predicted site: 13 (50.00%)
Max nb of predicted sites per peak: 5
(chr15:88954143-88955426)
Mean nb of predicted sites per peak: 1.38

[ sites: text ]
[ distribution: text ]
[ sites per peak: text ]
[ enrichment: text graph ]

Motif 6 oligos_7nt_mkv2_m1

k-mer sig=19.35; evalue=4.5e-20

mmmsCCGCSGCSGCGGskkg

CMMSCCGCSGCSGCGGSKKK

[ k-mers: statistics assemblies ]
[ matrix: tab_format transfac_format ]

JASPAR2024_CORE_vertebrates_non-redundant

name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match

columns aligned correlation cor mmmsCCGCSGCSGCGGskkg

ZNF93 MA1721.2 D 14 0.7000 0.730 0.511 NA NA

Total matches= 1

[ match table: html text ]
[ alignments (logos): html text ]

Predicted sites on test peaks

Distribution of sites

Nb of predicted sites per peak

Nb peaks with at least one predicted site: 2 (7.69%)
Max nb of predicted sites per peak: 115
(chr1:144076366-144077773)
Mean nb of predicted sites per peak: 63.50

[ sites: text ]
[ distribution: text ]
[ sites per peak: text ]
[ enrichment: text graph ]

Motif 7 oligos_7nt_mkv2_m2

k-mer sig=19.35; evalue=4.5e-20

GRGCAAAAaGCCGCGGCGGsSrr

YYSSCCGCCGCGGCTTTTTGCYC

[ k-mers: statistics assemblies ]
[ matrix: tab_format transfac_format ]

JASPAR2024_CORE_vertebrates_non-redundant

name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match

columns aligned correlation cor GRGCAAAAaGCCGCGGCGGsSrr

Total matches= 0

No match

Predicted sites on test peaks

Distribution of sites

Nb of predicted sites per peak

Nb peaks with at least one predicted site: 2 (7.69%)
Max nb of predicted sites per peak: 67
(chr1:144076366-144077773)
Mean nb of predicted sites per peak: 35.00

[ sites: text ]
[ distribution: text ]
[ sites per peak: text ]
[ enrichment: text graph ]

Motif 8 oligos_7nt_mkv2_m3

k-mer sig=16.86; evalue=1.4e-17

ccCSCCGCCGCsGCk

MGCSGCGGCGGSGGG

[ k-mers: statistics assemblies ]
[ matrix: tab_format transfac_format ]

JASPAR2024_CORE_vertebrates_non-redundant

name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match

columns aligned correlation cor ccCSCCGCCGCsGCk

PATZ1 MA1961.2 R 11 0.7333 0.821 0.602 NA NA

ZNF93 MA1721.2 R 11 0.6111 0.843 0.515 NA NA

ZIC4 MA0751.2 D 12 0.7059 0.707 0.499 NA NA

Total matches= 17 (14 more)

[ match table: html text ]
[ alignments (logos): html text ]

Predicted sites on test peaks

Distribution of sites

Nb of predicted sites per peak

Nb peaks with at least one predicted site: 3 (11.54%)
Max nb of predicted sites per peak: 91
(chr1:144076366-144077773)
Mean nb of predicted sites per peak: 36.33

[ sites: text ]
[ distribution: text ]
[ sites per peak: text ]
[ enrichment: text graph ]

Motif 9 oligos_7nt_mkv2_m4

k-mer sig=2.97; evalue=0.0011

mmGCCGcGGCGGs

SCCGCCGCGGCKK

[ k-mers: statistics assemblies ]
[ matrix: tab_format transfac_format ]

JASPAR2024_CORE_vertebrates_non-redundant

name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match

columns aligned correlation cor mmGCCGcGGCGGs

ZNF93 MA1721.2 D 12 0.8000 0.712 0.570 NA NA

SP2 MA0516.3 D 8 0.5714 0.795 0.454 NA NA

SP1 MA0079.5 D 8 0.5714 0.783 0.448 NA NA

Total matches= 8 (5 more)

[ match table: html text ]
[ alignments (logos): html text ]

Predicted sites on test peaks

Distribution of sites

Nb of predicted sites per peak

Nb peaks with at least one predicted site: 3 (11.54%)
Max nb of predicted sites per peak: 108
(chr1:144076366-144077773)
Mean nb of predicted sites per peak: 41.00

[ sites: text ]
[ distribution: text ]
[ sites per peak: text ]
[ enrichment: text graph ]

Motif 10 oligos_7nt_mkv2_m5

k-mer sig=1.72; evalue=0.019

sbCCCACCCcs

SGGGGTGGGVS

[ k-mers: statistics assemblies ]
[ matrix: tab_format transfac_format ]

JASPAR2024_CORE_vertebrates_non-redundant

name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match

columns aligned correlation cor sbCCCACCCcs

PATZ1 MA1961.2 R 11 1.0000 0.837 0.837 NA NA

KLF5 MA0599.1 D 10 0.9091 0.867 0.789 NA NA

KLF16 MA0741.1 D 11 1.0000 0.727 0.727 NA NA

Total matches= 40 (37 more)

[ match table: html text ]
[ alignments (logos): html text ]

Predicted sites on test peaks

Distribution of sites

Nb of predicted sites per peak

Nb peaks with at least one predicted site: 8 (30.77%)
Max nb of predicted sites per peak: 11
(chr1:144076366-144077773)
Mean nb of predicted sites per peak: 3.38

[ sites: text ]
[ distribution: text ]
[ sites per peak: text ]
[ enrichment: text graph ]

Predicted sites on test peaks (all motifs)

[tab]
[bed]

Word significance table
Word comparisons		[tab] [html] [heatmap]
Comparisons between discovered motifs
Discovered motifs versus discovered motifs		[ Discovered motif(s): tf ] [ table: html txt ] [ alignments (logo): html text ] [ clustering: html ] [ graph: gml (for CytoScape) ]
Discovered motifs versus transcription factor databases
Motifs versus JASPAR2024_CORE_vertebrates_non-redundant database		[ table: html txt ] [ alignments (logo): html text ] [ graph: gml (for CytoScape) ]

Log files
Parameters and files		[txt] [html]
Time log		[time table] [time log] [html]

Thomas-Chollier M, Herrmann C, Defrance M, Sand O, Thieffry D, van Helden J. (2012). RSAT peak-motifs: motif analysis in full-size ChIP-seq datasets. Nucleic Acids Res 40(4): e31.
Thomas-Chollier M, Darbo E, Herrmann C, Defrance M, Thieffry D, van Helden J. (2012). A complete workflow for the analysis of full-size ChIP-seq (and similar) data sets using peak-motifs. Nat Protoc 7(8): 1551-1568.

RSAT - peak-motifs result

Analysis: Astrocytes_MDD_off_on_drugs_down (16/05/2025 18:37)

Command

Sequence composition

Discovered motifs (by algorithm)

Discovered motifs (with motif comparison)

JASPAR2024_CORE_vertebrates_non-redundant

name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match

columns aligned correlation cor mmsCCGCSGCSGCGGskk

ZNF93 MA1721.2 D 14 0.7778 0.718 0.558 NA NA

Total matches= 1

JASPAR2024_CORE_vertebrates_non-redundant

name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match

columns aligned correlation cor mmGCCGmGGCkk

Zfx MA0146.3 D 10 0.8333 0.722 0.601 NA NA

ZNF213 MA2121.1 D 10 0.7143 0.732 0.523 NA NA

Total matches= 2

JASPAR2024_CORE_vertebrates_non-redundant

name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match

columns aligned correlation cor CaAAAAGCCGCG

Total matches= 0

JASPAR2024_CORE_vertebrates_non-redundant

name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match

columns aligned correlation cor mmmsCCGCSGCSGCGGskkg

ZNF93 MA1721.2 D 14 0.7000 0.730 0.511 NA NA

Total matches= 1

JASPAR2024_CORE_vertebrates_non-redundant

name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match

columns aligned correlation cor GRGCAAAAaGCCGCGGCGGsSrr

Total matches= 0

Motif locations (sites)

Motif comparisons

Logs and parameter files

Publications

Results

RSAT - peak-motifs result

Analysis: Astrocytes_MDD_off_on_drugs_down (16/05/2025 18:37)

Command

Sequence composition

Discovered motifs (by algorithm)

Discovered motifs (with motif comparison)

JASPAR2024_CORE_vertebrates_non-redundant name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match columns aligned correlation cor mmsCCGCSGCSGCGGskk ZNF93 MA1721.2 D 14 0.7778 0.718 0.558 NA NA Total matches= 1

JASPAR2024_CORE_vertebrates_non-redundant name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match columns aligned correlation cor mmGCCGmGGCkk Zfx MA0146.3 D 10 0.8333 0.722 0.601 NA NA ZNF213 MA2121.1 D 10 0.7143 0.732 0.523 NA NA Total matches= 2

JASPAR2024_CORE_vertebrates_non-redundant name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match columns aligned correlation cor CaAAAAGCCGCG Total matches= 0

JASPAR2024_CORE_vertebrates_non-redundant name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match columns aligned correlation cor mmmsCCGCSGCSGCGGskkg ZNF93 MA1721.2 D 14 0.7000 0.730 0.511 NA NA Total matches= 1

JASPAR2024_CORE_vertebrates_non-redundant name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match columns aligned correlation cor GRGCAAAAaGCCGCGGCGGsSrr Total matches= 0

Motif locations (sites)

Motif comparisons

Logs and parameter files

Publications

Results

JASPAR2024_CORE_vertebrates_non-redundant

name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match

columns aligned correlation cor mmsCCGCSGCSGCGGskk

ZNF93 MA1721.2 D 14 0.7778 0.718 0.558 NA NA

Total matches= 1

JASPAR2024_CORE_vertebrates_non-redundant

name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match

columns aligned correlation cor mmGCCGmGGCkk

Zfx MA0146.3 D 10 0.8333 0.722 0.601 NA NA

ZNF213 MA2121.1 D 10 0.7143 0.732 0.523 NA NA

Total matches= 2

JASPAR2024_CORE_vertebrates_non-redundant

name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match

columns aligned correlation cor CaAAAAGCCGCG

Total matches= 0

JASPAR2024_CORE_vertebrates_non-redundant

name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match

columns aligned correlation cor mmmsCCGCSGCSGCGGskkg

ZNF93 MA1721.2 D 14 0.7000 0.730 0.511 NA NA

Total matches= 1

JASPAR2024_CORE_vertebrates_non-redundant

name id strand Nb overlap % Pearson Normalized aligned col. motif aligned col. match

columns aligned correlation cor GRGCAAAAaGCCGCGGCGGsSrr

Total matches= 0